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Vladimir A Mitkevich Selected Research

Amyloid beta-Peptides

1/2024Post-translational modifications of beta-amyloid alter its transport in the blood-brain barrier in vitro model.
12/2023Switching On/Off Amyloid Plaque Formation in Transgenic Animal Models of Alzheimer's Disease.
4/2023Effect of β-amyloid on blood-brain barrier properties and function.
12/2022Distinct Effects of Beta-Amyloid, Its Isomerized and Phosphorylated Forms on the Redox Status and Mitochondrial Functioning of the Blood-Brain Barrier Endothelium.
1/2022Na,K-ATPase Acts as a Beta-Amyloid Receptor Triggering Src Kinase Activation.
1/2021Pharmacokinetics and Molecular Modeling Indicate nAChRα4-Derived Peptide HAEE Goes through the Blood-Brain Barrier.
10/2020Amyloid-β peptides slightly affect lifespan or antimicrobial peptide gene expression in Drosophila melanogaster.
7/2020Aberrant interactions between amyloid-beta and alpha5 laminins as possible driver of neuronal disfunction in Alzheimer's disease.
1/2020The English (H6R) Mutation of the Alzheimer's Disease Amyloid-β Peptide Modulates Its Zinc-Induced Aggregation.
1/2016Direct interaction of beta-amyloid with Na,K-ATPase as a putative regulator of the enzyme function.

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Vladimir A Mitkevich Research Topics

Disease

25Alzheimer Disease (Alzheimer's Disease)
01/2024 - 01/2016
10Neoplasms (Cancer)
12/2023 - 06/2007
9Amyloid Plaque
01/2024 - 09/2016
5Hypoxia (Hypoxemia)
01/2019 - 09/2012
4Neuroblastoma
01/2022 - 01/2016
3Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
01/2014 - 07/2010
2Neurodegenerative Diseases (Neurodegenerative Disease)
10/2023 - 10/2020
2Infections
01/2023 - 10/2020
2Heart Diseases (Heart Disease)
12/2022 - 12/2021
2Neoplasm Metastasis (Metastasis)
11/2020 - 07/2013
2Non-Hodgkin Lymphoma (Lymphosarcoma)
11/2020 - 07/2013
2Amyloidosis
01/2018 - 01/2018
2Melanoma (Melanoma, Malignant)
12/2017 - 07/2013
1Adenocarcinoma
12/2023
1Inborn Genetic Diseases (Disease, Hereditary)
12/2023
1Experimental Melanoma
12/2023
1Glaucoma
04/2023
1Glioblastoma (Glioblastoma Multiforme)
01/2023
1Cardiomyopathies (Cardiomyopathy)
12/2022
1Dilated Cardiomyopathy (Cardiomyopathy, Congestive)
12/2022
1Hypertension (High Blood Pressure)
12/2021
1Neuroinflammatory Diseases
12/2021
1Memory Disorders (Memory Loss)
08/2021
1Williams Syndrome (Williams-Beuren Syndrome)
12/2020
1Uterine Cervical Neoplasms (Cancer of the Cervix)
09/2017
1Carcinoma (Carcinomatosis)
09/2017
1Virus Diseases (Viral Diseases)
01/2016
1Lewis Lung Carcinoma
07/2013
1Leukemia
12/2011
1Hypersensitivity (Allergy)
06/2007

Drug/Important Bio-Agent (IBA)

16Amyloid (Amyloid Fibrils)IBA
12/2023 - 01/2016
14Peptides (Polypeptides)IBA
01/2024 - 01/2016
10Amyloid beta-PeptidesIBA
01/2024 - 01/2016
6Proteins (Proteins, Gene)FDA Link
08/2021 - 01/2016
5IonsIBA
12/2023 - 01/2016
5ZincIBA
07/2023 - 01/2017
5Adenosine Triphosphatases (ATPase)IBA
01/2022 - 01/2016
5Ribonucleases (Ribonuclease)IBA
11/2020 - 06/2007
5ribonuclease T(2)IBA
11/2020 - 10/2007
4Protein Isoforms (Isoforms)IBA
07/2023 - 10/2022
2InterferonsIBA
01/2023 - 09/2017
2src-Family KinasesIBA
01/2022 - 01/2016
2Glutathione Disulfide (GSSG)FDA LinkGeneric
01/2019 - 10/2017
2EnzymesIBA
10/2017 - 01/2016
1CopperIBA
12/2023
1Isoaspartic Acid (Isoaspartate)IBA
07/2023
1ProteomeIBA
04/2023
1Biomarkers (Surrogate Marker)IBA
04/2023
1MetalsIBA
04/2023
1Angiotensin-Converting Enzyme 2IBA
01/2023
1TroponinIBA
12/2022
1TropomyosinIBA
12/2022
1Trinitrotoluene (TNT)IBA
12/2022
1Troponin T (Troponin T1)IBA
12/2022
1AcidsIBA
12/2021
1Antiviral Agents (Antivirals)IBA
12/2021
1LigandsIBA
08/2021
1MethyltransferasesIBA
12/2020
1MicroRNAs (MicroRNA)IBA
11/2020
1Adenosine Monophosphate (AMP)IBA
10/2020
1Antimicrobial PeptidesIBA
10/2020
1AntibodiesIBA
07/2020
1Laminin (Merosin)IBA
07/2020
1Histidine (L-Histidine)FDA Link
01/2020
1Nicotinic Receptors (Nicotinic Acetylcholine Receptor)IBA
01/2019
1S-ethyl glutathioneIBA
01/2019
1Acetylcysteine (Siran)FDA LinkGeneric
01/2019
1Sulfhydryl Compounds (Thiols)IBA
01/2019
1Cholinergic Agents (Cholinergics)IBA
01/2019
1UbiquitinIBA
01/2019
1S-NitrosoglutathioneIBA
01/2019
1Proteasome Endopeptidase Complex (Proteasome)IBA
01/2019
1Etoposide (VP 16)FDA LinkGeneric
08/2018
1Caspase 3 (Caspase-3)IBA
08/2018
1thioflavin TIBA
01/2018
1Trace Elements (Biometals)IBA
01/2018
1Carrier Proteins (Binding Protein)IBA
01/2018
1Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA
01/2018
1Doxorubicin (Adriamycin)FDA LinkGeneric
12/2017
1Cytostatic AgentsIBA
12/2017
1Peptide FragmentsIBA
12/2017
1Cysteine (L-Cysteine)FDA Link
10/2017
1Cardiac GlycosidesIBA
10/2017
1Oncogene Proteins (Oncogene Protein)IBA
09/2017
1Viral ProteinsIBA
09/2017
1Protein AggregatesIBA
09/2016
1SodiumIBA
01/2016
1PotassiumIBA
01/2016
1ribonuclease Sa3IBA
01/2014
1Caspase 8 (Caspase-8)IBA
07/2013
1Adenosine Triphosphate (ATP)IBA
09/2012
1Toxic ActionsIBA
12/2011
1Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
07/2010
1Proto-Oncogene Proteins c-kit (Proto-Oncogene Protein c-kit)IBA
07/2010
1RNA (Ribonucleic Acid)IBA
01/2010

Therapy/Procedure

4Therapeutics
12/2021 - 06/2007
2Intraperitoneal Injections
11/2020 - 07/2013
1Intravenous Injections
01/2018
1Injections
01/2018